\(\mathbf i\) component: \(2\cdot6-3\cdot5=-3\); \(\mathbf j\) component: \(-(1\cdot6-3\cdot4)=6\); \(\mathbf k\) component: \(1\cdot5-2\cdot4=-3\). The middle term of the expansion carries a minus sign.
The cross product of two vectors \(\mathbf u\) and \(\mathbf v\) in \(\mathbb R^3\) is the vector perpendicular to both whose length is the area of the parallelogram they span, oriented by the right-hand rule.