By distributivity, \(\mathbf u\times(2\mathbf v+3\mathbf u)=2(\mathbf u\times\mathbf v)+3(\mathbf u\times\mathbf u)\) and \(\mathbf u\times\mathbf u=\mathbf 0\). What remains is \(2\langle1,2,2\rangle\).
The cross product of two vectors \(\mathbf u\) and \(\mathbf v\) in \(\mathbb R^3\) is the vector perpendicular to both whose length is the area of the parallelogram they span, oriented by the right-hand rule.